Table 1.

Summary of in vitro properties of PSMA-targeted ProCAs

Contrast agent	ProCA32.wp	ProCA32.562	ProCA32.PSMA
r1 (mM−1 S−1)	24.4 ± 0.08	21.5 ± 0.2	27.6 ± 0.9
r2 (mM−1 S−1)	33.5 ± 0.1	29.8 ± 0.3	37.9 ± 1.1
Kd (Tb3+) (M)	6.8 ± 0.2 × 10−22	2.5 ± 0.3 × 10−22	3.3 ± 0.3 × 10−22
Kd (Gd3+) (M)	2.4 ± 0.3 × 10−22	1.3 ± 0.1 × 10−22	0.9 ± 0.1 × 10−22
Kd (Ca2+) (M)	1.2 ± 0.03 × 10−8	1.4 ± 0.01 × 10−8	1.7 ± 0.02 × 10−8
Kd (Zn2+) (M)	1.4 ± 0.03 × 10−6	2.5 ± 0.05 × 10−6	1.6 ± 0.04 × 10−6
Kd (PSMA) (μM)			1.1 ± 0.1