Table 3.

Biological functions of the genes that responded in at least 3 of the 5 cell lines tested.

Biological function	Induced genes	Repressed genes
Cell cycle regulation	CDKN1A, MDM2, PPM1D, PSMB4, PTP4A1, SESN1, SESN2	ASPM, AURKA, AURKB, BUB1, C13orf34 (BORA), MIS18BP1, C15orf23 (SKAP), C9orf140 (p42.3), CCNB1, CCNF, CDC20, CDC25C, CDCA3, CENPA, CENPE, CKS2, FAM83D, GSPT1, GTSE1, HJURP, KIF18A, KIF20A, KIF23, NEK2, PLK1, PSRC1, SGOL2, WEE1, XPO
DNA repair	BTG2, DDB2, GADD45A, POLH, REV3L, RRM2B, XPC
Apoptosis	ARHGEF3, CYFIP2, DRAM, FAS, PHLDA3, RPS27L, TP53INP1, ZMAT3	G2E3
Transcriptional regulation	ATF3, C5orf41, TRIM22	CDCA7, DEPDC1
Other/uncharacterized	ANKRA2, ASCC3, C12orf5, CCDC90B, DCP1B, DGKA, ENC1, F2R, FBXW7, FDXR, FEZ1, FST, GDF15, GREB1, KLHL24, C20orf107, LOC643401, LOC727770, LOC727916, ORAI3, PANK1, PGF, PLCXD2, PLK3, PRKX, RNF19B, RPS11, SERTAD1, TMEM68, TOB1	CKAP2L, EIF4A1, FAM72A, GPSM2, KIF14, LRRC8C, PIF1, SLC20A1, TNIK, TRIB1, TROAP