Figure 5.

Membrane integrity assay. HER14 cells were incubated with propidium iodide and SA1641 (red symbols) or digitonin (blue symbols) (0–24 μM). The saponin induced influence on membrane permeability was determined by measuring the uptake of PI into the cells using flow cytometry. Y‐achsis represents medians of the fluorescence histograms. Compared to digitonin, SA1641 exhibited no membrane permeabilizing effects. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)