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SA1641‐mediated efficacy increase of different targeted toxins
| SI50 (nM)a | TEFb | ||
|---|---|---|---|
| Without SA1641 | With SA1641 | ||
| RTA‐EGF | >1000 | 61 | 16.3 |
| DT390EGF | 8.8 | 0.73 | 12 |
| EGF‐ETA' | 128 | 103 | 1.2 |
| Dianthin‐30‐EGF | 0.45 | <0.000 0001 | >4,000,000 |
| Saporin‐EGF | 57 | <0.000 0001 | >4,000,000 |
50% cell survival.
TEF, toxicity enhancement factor (SI50 without SA1641/SI50 with SA1641), represents the x‐fold SA1641‐mediated efficacy increase of targeted toxins.
