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Illustration of the elements responsible for an effective antitumor immune response: cyclophosphamide (CTX), adoptive transfer of tumor‐immune lymphocytes (ACT) and tumor lysate (Ag) must be combined to reject a subsequent tumor challenge (panel a). Six days is the time interval necessary to mature an effective antitumor response to reject tumor (panel b). The detailed results of the experiment are reported elsewhere (Proietti et al., 1998).
