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. 2012 Oct 13;7(1):112–120. doi: 10.1016/j.molonc.2012.09.002

Figure 5.

Figure 5

The anti‐tumor effect of gefitinib and AZD6244 or CI‐1040 in the mouse xenograft model. (A) PC‐9/Wt xenografts were treated with vehicle (●), AZD6244 (▵), gefitinib (○), or a combination of both (▾). (B) PC‐9/gefB4 xenografts were treated with vehicle (●), AZD6244 (▵), gefitinib (○), or a combination of both (▾). (C) PC‐9/Wt xenografts were treated with vehicle (●), gefitinib (○), or a combination of gefitinib and CI‐1040 (▾). (D) PC‐9/Gef B4 xenografts were reated with vehicle (●), gefitinib (○), or a combination of gefitinib and CI‐1040 (▾). Tn/T0: Tumor size on day n over tumor size on day 0 of drug treatment. Values are the mean ± S.E.M. (n = 4–9).