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. 2013 Jul 20;7(6):1012–1018. doi: 10.1016/j.molonc.2013.07.010

Figure 5.

Figure 5

Nelfinavir causes mTOR inhibition in cancer cells. MDA‐MB‐453 and OVCAR3 cells were incubated with 15 μg/mL nelfinavir for the indicated periods and subjected to Western blot analysis. mTOR inhibition was shown by reduced ribosomal protein S6 phosphorylation and hypophosphorylation (faster migration) of 4E‐BP1.