Table 2.
Associations between LPCAT1 expression results and ERG negative prostate cancer phenotype.
| Parameter | n Evaluable | LPCAT1 IHC result | p value | |||
|---|---|---|---|---|---|---|
| Negative (%) | Weak (%) | Moderate (%) | Strong (%) | |||
| All cancers | 4.761 | 39.36 | 19.3 | 24.66 | 16.68 | |
| Tumor stage | ||||||
| pT2 | 3.225 | 42.73 | 20.12 | 23.41 | 13.74 | <0.0001 |
| pT3a | 958 | 36.12 | 18.16 | 25.47 | 20.25 | |
| pT3b | 532 | 25.56 | 16.17 | 30.45 | 27.82 | |
| pT4 | 28 | 25 | 25 | 21.43 | 28.57 | |
| Gleason grade | ||||||
| ≤3 + 3 | 1.112 | 52.16 | 19.15 | 17.9 | 10.79 | <0.0001 |
| 3 + 4 | 2.646 | 38.7 | 20.26 | 24.87 | 16.18 | |
| 4 + 3 | 727 | 28.89 | 17.47 | 31.22 | 22.42 | |
| ≥4 + 4 | 252 | 20.24 | 15.48 | 32.94 | 31.35 | |
| Lymph node metastasis | ||||||
| N0 | 2.691 | 36.94 | 19.73 | 25.12 | 18.21 | <0.0001 |
| N+ | 236 | 20.76 | 17.37 | 36.44 | 25.42 | |
| Surgical margin | ||||||
| negative | 3.819 | 40.35 | 19.46 | 24.38 | 15.82 | 0.006 |
| positive | 856 | 35.51 | 18.57 | 25.82 | 20.29 | |