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. 2013 Jun 13;7(5):955–967. doi: 10.1016/j.molonc.2013.05.005

Figure 6.

Figure 6

SPRR3 expression correlated with radiosensitivity of esophageal cancer. A) SPRR3 protein was detected by immunohistochemistry staining in the pretreatment biopsies in radiotherapy alone group (left panel). SPRR3 expression correlated with response of radiotherapy (P = 0.007, right panel). Response: cases with complete response and partial response after radiotherapy; No response: cases with stable disease and progress disease after radiotherapy. B) Overall survival of patients according to the expression of SPRR3 using Kaplan–Meier curve. Patients with SPRR3 expression (26 cases) had significantly higher survival rates than patients lacking SPRR3 expression (50 cases, P = 0.008). C) SPRR3 expression associated with esophageal cancer recurrence in radiotherapy alone group (P = 0.017). Six cases were excluded since recurrence was unknown. D) SPRR3 expression was associated with pathologic complete response to preoperative radiotherapy (P = 0.035). PathCR, complete pathologic response; No pathCR, less than complete pathologic response.