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Rucaparib plus radiotherapy as inducer of mitotic catastrophe. MiaPaCa‐2 cells were incubated with 1 μM Rucaparib and after 24 h were exposed to a radiation dose of 10 Gy for 24 h. (A) MNs and NBUDs were highlighted by the cytokinesis‐block micronucleus assay (arrows). (B) Protein extracts were analysed by western blotting. The amount of p‐Akt and p53 was determined using β‐actin to normalize values.
