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. 2014 May 27;8(8):1365–1378. doi: 10.1016/j.molonc.2014.05.008

Figure 8.

Figure 8

Schematic overview of the signaling events that link the two pro‐metastatic agents IL‐6 and WNT5A in melanoma. The broken arrow indicates a mechanism demonstrated by other researchers that together with the present findings suggests a positive feed back‐loop whereby WNT5A indirectly could regulate its own expression level.