Table 2.
5‐year and 8‐year Overall Survival (OS) rates according to treatment and TP53 mutation status.
| Wild type T53 | Treatment arm | Observation arm | Both arms | |||
|---|---|---|---|---|---|---|
| Rate (a) | [95% CI] | Rate (a) | [95% CI] | Rate (a) | [95% CI] | |
| 5 year survival | 49% | 41 %–57% | 47% | 39 %–54% | 48% | 42 %–53% |
| 8 year survival | 35% | 26 %–43% | 45% | 37 %–53% | 41% | 35%–46% |
| Median survival (years) | 4.8 | 4.4 | 3.2 | |||
| Mutant TP53 | ||||||
| 5 year survival | 34% | 26 %–43% | 45% | 35 %–55% | 39% | 33 %–46% |
| 8 year survival | 24% | 16 %–33% | 40% | 29 %–50% | 31% | 24 %–38% |
| Median survival (years) | 2.6 | 3.5 | 3.1 | |||
| Total | ||||||
| 5 year survival | 42% | 36 %–48% | 41% | 40 %–52% | ||
| 8 year survival | 30% | 24 %–36% | 36% | 37 %–50% | ||
| Median survival (years) | 3.1 | 3.3 | ||||
(a) Estimated with Kaplan–Meier method.