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. 2014 Oct 5;9(2):422–436. doi: 10.1016/j.molonc.2014.09.010

Figure 2.

Figure 2

Kaplan–Meier survival curves. Overall Survival of HGSOCs from the discovery series according to (A) clusters defined by DNA copy number‐based unsupervised analysis (log‐rank P = 0.003) and (B) the presence of the 6q24.2–26 deletion (log‐rank P = 0.001). Validation of the association observed between the presence of the 6q24.2–26 deletion and improved 5‐year survival in two independent series from (C) sporadic HGSOCs where the deletion was evaluated by Fluorescence in situ Hybridization (log‐rank P = 0.04) and (D) HGSOC patients from the TCGA study (log‐rank test P = 0.001). Lower expression of the genes within 6q24.2–26 region predicts longer Overall Survival in (E) 799 HGSOCs (log‐rank P = 0.002) and in (F) 675 High‐FIGO HGSOC carcinomas (log‐rank P = 0.02), as shown using an online tool KM‐plotter from publicly‐available microarray data (Gyorffy et al., 2012).