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. 2014 Sep 6;9(1):282–294. doi: 10.1016/j.molonc.2014.08.012

Figure 1.

Figure 1

The co‐RNAi of HER2 and PTK6 additively reduces the phosphorylation of tumour‐promoting proteins and the migration of BT474 cells. A, Western blot analysis of HER2, PTK6, HER3, IGF‐1R, (p = phospho) ERK5, (p) STAT3, (p) Akt, (p) PTEN, (p) p38MAPK, (p) ERK1/2 and tubulin (loading control). For quantification, the means of three independent experiments were calculated in relation to the mock control. B, The graphs illustrate the means of the percentages of the open areas derived from three experiments; SDs and p‐values are shown. The scale bars represent 400 μm.