Table 2.
Multivariate Cox regression analysis of survival according to ASAH1 expression and molecular subtypes and standard parameters.
| Parameter | Numbersa | HR | 95% CI | P‐value |
|---|---|---|---|---|
| ASAH1 (High vs. Low) | 107 vs. 763 | 0.71 | 0.47–1.06 | 0.090 |
| Lymph node status (LNN vs. N+) | 662 vs. 208 | 0.81 | 0.61–1.08 | 0.15 |
| Age (>50 vs. ≤50) | 466 vs. 404 | 1.13 | 0.90–1.43 | 0.29 |
| tumor size (≤1 cm vs. >1 cm) | 238 vs. 632 | 0.91 | 0.69–1.20 | 0.50 |
| Histological grading (G3 vs. G1&G2) | 484 vs. 386 | 1.05 | 0.82–1.34 | 0.71 |
| Molecular subtype: TNBC | 261 | <0.001 | ||
| HER2 | 91 | 0.94 | 0.61–1.44 | 0.77 |
| LumA | 255 | 0.68 | 0.48–0.97 | 0.031 |
| LumB | 263 | 1.40 | 1.05–1.86 | 0.023 |
a
Information on all six parameters was available for 870 of the 2590 samples with follow up data.