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. 2015 Sep 30;10(2):195–212. doi: 10.1016/j.molonc.2015.09.008

Table Table 2.

Clinical correlation of 5‐HT2A gene expression in HCC.

Clinicopathological features Frequency (%) Receptor 5‐HT2A P value
Mean ± SD/number of patients
Overexpression
+
Age (year) 0.101
<53 15 (45.5) 13 2
≥53 18 (54.5) 11 7
Sex 0.191
Male 29 (87.9) 20 9
Female 4 (12.1) 4 0
Non‐tumorous liver histology 0.031 ∗
Non‐cirrhotic 2 (6.1) 0 2
Chronic hepatitis 16 (48.5) 11 5
Cirrhotic 15 (45.5) 13 2
Tumour size (cm) a 0.202
<5 9 (27.3) 8 1
≥5 24 (72.7) 16 8
Tumour recurrence 0.825
Absence 12 (36.4) 9 3
Presence 21 (63.6) 15 6
Venous infiltration b 0.475
Absence 15 (45.5) 10 5
Presence 18 (54.5) 14 4
Number of tumour nodules 0.097
1 25 (75.8) 20 5
≥2 8 (24.2) 4 4
Cellular differentiation c,d 0.524
Well differentiated 11 (33.3) 9 2
Moderately differentiated 14 (42.4) 10 4
Poorly differentiated 7 (21.2) 4 3
AJCC stage 0.392
I and II 15 (45.5) 12 3
III and IV 18 (54.5) 12 6

*P < 0.05.

Tumour size was defined as the length of the largest tumour nodule.

Venous infiltration was defined based on findings by microscopic and major pathologic examination.

Well differentiated (Edmonson grade 0–2); moderately differentiated (Edmonson grade 3); poorly differentiated (Edmonson grade 4).

Partial data is not available and statistics were based on available data of 32 patients.