Table 5. Logistic regression of clinical and cytokine level variables.
Variable |
crude OR |
CIor |
ORmodel 1 (IL-6 and respiratory distress) |
CIor |
ORmodel 2 (IL-6, respiratory distress and increased hematocrit) |
CIor |
---|---|---|---|---|---|---|
Fever a | 1.0 | - | ||||
Gastrointestinal symptoms | 1.2 | 0.3–4.7 | ||||
Headache | 0.6 | 0.1–4.1 | ||||
Myalgia | 1.3 | 0.3–6.8 | ||||
Respiratory distress a | 1.0 | - | 1.0 | - | 1.0 | - |
Infiltrate on chest X-Ray | 0.4 | 0.1–1.8 | ||||
Blood shift | 0.3 | 0.1–1.6 | ||||
Atypical lymphocytosis | 2.2 | 0.2–26 | ||||
Thrombocytopenia | 1.5 | 0.2–10 | ||||
Increased hematocrit* | 3.8 | 1–14.2 | 6.9 | 0.8–54.9 | ||
IL-1β | 0.4 | 0.4–5.4 | ||||
IL-12p70 | 0.3 | 0.3–3.0 | ||||
IL-21 | 0.5 | 0.1–2.4 | ||||
TNF-α | 1.6 | 0.5–5.7 | ||||
IFN-γ | 1.4 | 0.4–4.8 | ||||
IL-10 | 2.0 | 0.6–6.9 | ||||
IL-6* | 14.4 | 3.3–63.1 | 10 | 1.6–74.7 | 10.9 | 1.6–74.7 |
a OR not calculated because one or more boxes contain zero.
* Significant
OR model 1: Stepwise Forward
OR model 2: Stepwise Reverse