Table 2.
Presence of fracture in hospitalized orthogeriatric patients according to serum P1NP/βCTX ratio tertiles
| P1NP/βCTX ratio | Model 1a
|
Model 2b
|
||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | OR | 95% CI | P-value | |
| Hip fracture | ||||||
| Tertile 1 (<78.6), n=221 (48.1%) | 3.44 | 2.32–5.12 | 0.000 | 3.05 | 2.02–4.63 | 0.000 |
| Tertile 2 (78.6–129.2), n=140 (30.8%) | 1.62 | 1.10–2.38 | 0.016 | 1.54 | 1.03–2.31 | 0.036 |
| Any fracture | ||||||
| Tertile 1 (<78.6), n=334 (39.1%) | 2.51 | 1.80–3.48 | 0.000 | 2.30 | 1.63–3.23 | 0.000 |
| Tertile 2 (78.6–129.2), n=287 (33.9%) | 1.61 | 1.19–2.18 | 0.002 | 1.56 | 1.14–2.13 | 0.005 |
Notes: Logistic regression models for fracture presence by tertiles of serum P1NP/βCTX ratio; as the reference used tertile 3 (P1NP/βCTX >129.2, the highest), n=94 (20.4%) in the hip fracture group and n=230 (27.0%) among all patients with fractures.
Adjustment only for age and gender.
Adjustment for age, gender, 25(OH)D, PTH, calcium (corrected for albumin), phosphate, magnesium, osteocalcin, albumin, alkaline phosphatase, GFR, presence of dementia, cardiovascular diseases (coronary artery disease, atrial fibrillation, and chronic heart failure), cerebrovascular diseases, diabetes mellitus, history of smoking, and alcohol consumption status.
Abbreviations: P1NP, N-terminal propeptide of type 1 procollagen; βCTX, cross-linked carboxy-terminal telopeptide of type 1 collagen; OR, odds ratio; CI, confidence interval.