Table 1.
Behavioral test | naive | non-dependent | dependent | ||
---|---|---|---|---|---|
CCL2-tg vs non-tg | CCL2-tg 2BC vs naive | non–tg 2BC vs naive | CCL2-tg CIE vs cont | non–tg CIE vs cont | |
Barnes Maze | |||||
-latency | No Δ | No Δ | No Δ | - | - |
-errors | No Δ | ↑ | No Δ | - | - |
-% target quadrant | No Δ | ↓ | No Δ | - | - |
Y-maze | |||||
-arm entries | No Δ | - | - | No Δ | No Δ |
- spont. alternations | No Δ | - | - | ↓ | No Δ |
-% spont. alternations | No Δ | - | - | ↓ | No Δ |
Context fear conditioning | No Δ | - | - | No Δ | ↓ |
Cued fear conditioning | No Δ | - | - | No Δ | ↓ |
Light/dark transfer | No Δ | - | - | No Δ | No Δ |
Forced-swim test | No Δ | - | - | No Δ | No Δ |
Note: In these tests the functional consequence for the ↓ or ↑ is impairment.