Table 1. Chemical structures and inhibitory properties of γ-secretase inhibitors and photoprobes used in this study.

Name	Structure	In vitro, nM
d–10	Boc–Val–Gly–Aib–Val–Val–Ile–Aib–Thr*–Val–Aib–OMe	100
d–13	Ac–Val–Gly–Aib–Val–Val–Ile–Aib–Thr*–Val–Aib–Val–Val–Aib–NH2	30
III–31–C		20
DAPT		10
Compound E		3
d–10–Bpa–Bt	Bt–Link–Val–Gly–Aib–Val–Val–Bpa–Aib–Thr*–Val–Aib–OMe	100
d–13–Bpa–Bt	Bt–Link–Val–Gly–Aib–Val–Val–Bpa–Aib–Thr*–Val–Aib–Val–Val–Aib–NH2	10
III–63		10