Figure 7.

Contractility of a cross-linked filament network driven by motors. Filaments are red, motors are black, and cross-linkers are green. (A) Shown here are network configurations at t = 0, 50, 150, and 398 s. Although all filaments are shown, only 10% of cross-linkers and 50% of motors are shown for clarity. (B) Given here is the radial distribution function at frames corresponding to (A). (C) Shown here is the quantification of the motion at t = 500 s. Arrows (directions and sizes) indicate the filament-bead velocity field generated by the procedure in Supporting Materials and Methods. Colors map the corresponding divergence. (D) Shown here is the density weighted divergence (blue filled circles; dA = (1 μm)²) and the average filament strain (red open circles) of actin filaments for contractile networks. Dark lines for both curves shows the mean μ(t) of these results at each time t over N = 20 simulations. Shaded areas show the SE of the mean $\mu \left(t\right)\pm \sigma \left(t\right)/\sqrt{N}$, where σ(t) is the SD. To see this figure in color, go online.