Fig. 2.
Wnt10b expression maintains bone in ovarectomized mice. (A) μCT of femurs from 4-month wild-type and FABP4-Wnt10b mice were either sham-operated or ovariectomized at 3 months of age. Morphometric variables analyzed include bone volume/total volume (B; BV/TV), trabecular number (C; Tb. N.), trabecular thickness (D; Tb. Th.), trabecular spacing (E; Tb.Sp.), and uterine weight (F). Statistical significance for each measurement was evaluated with Student's t test: P < 0.05 (*), < 0.01 (#), with n = 6–8 mice for each treatment.