Figure 2c:

MR elastography results and histologic analyses for the ARPKD mouse model. (a) Histologic analysis shows that mice with ARPKD had mild fibrosis but no observable portal inflammation after weaning (1 month old). They then developed mild inflammation and moderate fibrosis by 3 months. All control animals had normal histologic findings. (b, c) MR elastography results of liver stiffness (b) and damping ratio (c) at 80 Hz. Welch t tests were performed to compare mice with ARPKD and control mice at 1, 3, and 6 months of age. (The number of animals was 6:6 for each comparison.)