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Osteocalcin secretion. In cells exposed to hypoxia (5% O2) for 7 d followed by normoxia (21% O2) for 7 d (HN), the level of osteocalcin increased rapidly from day 10, peaking at day 12, as compared with cells in the other groups. NN, normoxia for 14 d; NH, normoxia for 7 d followed by hypoxia for 7 d; and HH, hypoxia for 14 d. aP < 0.05.
