Fig. 7.

Neutrophil infiltration after SCI is inhibited by UA treatment. CD1 mice were subjected to compression-induced SCI and treated with UA or saline as described in the legend to Fig. 2. Spinal cord tissues were collected 4 h after SCI, and tissue levels of MPO were determined as an indicator of neutrophil accumulation. Results are expressed as unit per gram of wet tissue (mean ± SEM) (n = 15 mice per group). ***, P < 0.001 compared with the sham-operated group by Student's unpaired t test. ###,P < 0.001 compared with the SCI plus saline group by Student's unpaired t test.