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Comparison of MHC-I bound peptides. The conformations of peptides bound by HLA-G (purple), HLA-E (48) (red), HLA-A2 (49) (yellow), and Qa-2 (39) (green) are shown in a side view (A), top view (B), and a view showing the main chain interactions between the epitope and the HLA-G hc (C). Polar interactions are depicted only (dashed lines); water molecules are shown in blue spheres.
