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. 2017 Jul 27;8:500. doi: 10.3389/fphar.2017.00500

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Copyright © 2017 Camerino, Musumeci, Conte, Musaraj, Fonzino, Barca, Marino, Rodolico, Tricarico, Camerino, Carratù, Desaphy, De Luca, Toscano and Pierno.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Real-time PCR analysis of mRNA expression level of genes involved in glucose metabolism and transporter genes in VL muscle biopsies of patients in therapy with statin showing sign of myopathy. Histograms show quantification of transcript levels for IRS1, and GLUT-4 normalized by the beta-2 microglobulin gene. In each graph, the bars represent the mean values ± SEM in myopathic subjects (Statin) compared with those of untreated subjects (Ctrl) from the number of subjects indicated in brackets. ^∗Significantly different with respect to the own control (P < 0.05) by Student’s t-test.