Table 1.

Physical and clinical characteristic of statin treated myopathic subjects analyzed in this study.

Subject examined	Sex/age (years)	Statin therapy	Dose (mg)	Duration of therapy (years)	Symptoms	CK UI/l	EMG	BM morphology
FG	M, 63	Pravastatin	40	4	Myalgia, cramps	350	Fibrillation potential	Atrophic fibers
GP	M, 54	Simvastatin	40	6	Myalgia, fatigability	2300	Normal	Increasing of Type II fibers
LMP	M, 60	Rosuvastatin	10	5	Myalgia, muscle weakness	400	Myopathic pattern	Fiber size Variability
MN	M, 57	Simvastatin +Ezetimibe	10/20	Several months	Myalgia	600	Myopathic pattern	Some fiber type grouping
MG	M, 71	Simvastatin	40	4	Myalgia	600	Normal	Fiber size variability
MM	F, 77	Simvastatin	40	3	Myalgia, muscle weakness	240	Myopathic pattern	Presence of some COX negative fibers
MC	M, 63	Simvastatin	40	2	Myalgia, easy fatigability	300–2000	Normal	Vacuoles with lipid storage
PS	M, 50	Simvastatin	20	6	Myalgia	167–800	Normal	Presence of some COX negative fibers
RN	M, 66	Fluvastatin	40	5	Myalgia, cramps	700–1700	Fibrillation potentials	Some fiber type grouping
VM	F, 64	Atorvastatin	40	1 month	Myalgia, exercise intolerance	600	Normal	Type II fiber atrophy