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. 2017 Jul 26;7:6595. doi: 10.1038/s41598-017-06632-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Computational modeling results for the complete WT EGFR structure. (A) The initial structure 2ITY. (B) The generated complete WT EGFR structure. (C) The segments of 3IKA (residues 858–879). (D) The segments of 3W2S (residues 987–1019). In (C,D), the yellow part (2ITY) and the grey part (3IKA or 3W2S) aligned very well. The red segments replaced the corresponding yellow segments to generate the complete WT EGFR structure.