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. 2017 Jul 26;7:6597. doi: 10.1038/s41598-017-06790-z

Table 1.

Gene Ontology analysis was performed using DAVID (https://david.ncifcrf.gov/) on H3K9ac-enriched genes in St Gallen molecular subtypes of breast cancer.

GO term name Luminal A Luminal B1 Luminal B2 TNBC HER2-positive
up down up down up down up down up down
Regulation of metabolic process 18 44 56 88 49 27 157 498 82 18
Regulation of cell process 22 62 83 121 59 40 217 492 110 9
Cell proliferation 10 24 32 15 10 40 88 28
Positive regulation of cell proliferation 9 16 17 7 19
Cell migration 5 18 26 17 28 61 23
Negative regulation of cell death 10 15 19 8 27 54 19
Negative regulation of programmed cell death 10 14 17 8 27 52 18
Regulation of signaling 22 38 38 75 156 40
Cell-cell signaling 6 17 34 38 13 16 43 32
Regulation of cell differentiation 16 21 40 20 11 45 79 32 9
Positive regulation of epithelial cell differentiation 2 4 3 6 4
Hormone-mediated signaling pathway 3 6 4 8 4

The number of differentially modified genes is shown.