Table 3.

Top 50 GSK-J4 down-regulated common genes in LPS treated PM and BV-2 microglial cells.

Gene symbol	PM_Down regulated genes (Log2 fold change)	P-value	BV-2_Down regulated genes (Fold change)	P-value
CD69	−7.59	2.3E-48	−5.96	2.7E-33
IFIT1BL1	−7.11	2.6E-28	−6.60	9.3E-32
NOS2	−6.89	3.7E-55	−1.84	3.5E-31
HDC	−6.87	1.7E-18	−3.02	1.7E-23
TNFSF10	−6.81	1.4E-63	−6.02	5.2E-24
MX1	−6.75	8.5E-206	−4.72	3.6E-53
BATF2	−6.49	1.0E-28	−1.84	4.7E-08
SLFN4	−6.46	1.1E-56	−6.20	6.4E-19
CCL12	−6.37	6.0E-42	−5.08	1.0E-17
IFI205	−6.01	2.7E-50	−2.72	1.9E-16
IGTP	−5.98	5.4E-04	−2.40	6.2E-43
IFI47	−5.55	2.7E-199	−2.96	4.8E-25
IFIT3	−5.27	4.8E-285	−3.44	3.1E-71
CMPK2	−5.22	5.9E-04	−2.48	7.6E-139
IFI44	−5.19	3.4E-236	−5.18	1.5E-16
IL1B	−4.97	3.2E-63	−2.86	1.6E-128
PHF11D	−4.88	1.5E-213	−2.80	5.0E-22
SLFN9	−4.86	7.3E-266	−2.82	1.5E-05
IRGM2	−4.74	5.7E-228	−1.64	3.4E-23
IRF7	−4.65	7.1E-83	−1.34	5.9E-18
USP18	−4.65	2.1E-102	−2.10	3.3E-57
IFIT2	−4.56	5.7E-83	−4.02	2.1E-33
SLFN5	−4.55	4.9E-100	−5.28	2.2E-15
IL6	−4.51	2.1E-99	−3.28	5.1E-45
CLEC2D	−4.51	5.2E-04	−2.86	9.9E-27
IFIT3B	−4.49	2.9E-128	−4.48	5.5E-26
SLFN8	−4.47	3.2E-06	−3.08	6.3E-12
TRIM30D	−4.45	1.9E-93	−4.24	3.9E-21
LCN2	−4.41	3.7E-22	−2.12	2.8E-27
IFI204	−4.40	5.9E-44	−2.62	3.5E-08
GBP2	−4.38	1.4E-227	−1.60	7.0E-48
ISG20	−4.30	1.4E-31	−1.82	4.7E-12
TLR3	−4.22	4.6E-46	−4.88	4.3E-13
MX2	−4.22	5.5E-150	−3.26	2.2E-24
GBP5	−4.17	1.3E-185	−2.10	5.1E-31
H2-T24	−4.10	1.1E-124	−2.46	2.5E-08
ZBP1	−4.10	8.6E-160	−2.12	3.0E-29
GBP7	−4.10	3.3E-302	−3.24	3.6E-19
CSF3	−4.06	5.8E-17	−3.02	4.8E-25
CXCL10	−3.90	1.2E-47	−2.70	1.9E-109
OASL2	−3.86	5.6E-57	−1.72	1.4E-45
SETDB2	−3.84	5.2E-96	−2.12	3.9E-09
STAT1	−3.81	9.2E-57	−1.84	2.0E-23
CCL7	−3.79	3.3E-128	−5.20	2.1E-57
RSAD2	−3.65	2.2E-04	−2.14	1.5E-116
MITD1	−3.64	7.1E-62	−2.72	5.2E-04
IRGM1	−3.62	3.2E-14	−2.08	1.5E-59
IRG1	−3.58	1.2E-08	−1.40	1.5E-156
PARP14	−3.56	1.9E-07	−1.94	8.8E-24