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. 2017 Jul 26;7:6548. doi: 10.1038/s41598-017-06738-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Global Expression Patterns in LRTI. (A) Shown is a heat map for the 141 genes (rows) demonstrating significantly different expression levels between bacterial and non-bacterial groups. Each column represents an individual subject, and subjects were grouped based upon microbiological diagnosis, using independent hierarchical clustering (Euclidean distance with average linkage). (B) The same data are presented, grouped by clinical diagnosis. The pink semi-circle denotes the patient with influenza A and a single blood culture positive for S. aureus.