Table 1.

Pharmacokinetics of ibuprofen in children [10]

Oral absorption	T 1/2: 0.3–0.9 h
	T max: 1–2 h
	10 mg kg−1 → C max: 44 mg L−1
Protein binding	99%
Active isomer	S(+)
Plasma concentration	S(+) children < adults
Metabolism	CYP450 2C9 and 2C8
T 1/2	0.9–2.3 h

T _1/2 half-life, T _max time to C_max, C _max maximum concentration, CYP450 cytochrome P450