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. 2017 Jul 26;7:6590. doi: 10.1038/s41598-017-06929-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Dynamic changes in the transcriptional regulatory network in response to drought stress. (a) Heatmap comparing scaled expression values of 94 differentially expressed transcription factors (TFs) at four developmental stages in three tissues. The genes listed on the right (GRMZM2G025642, GRMZM2G011357, GRMZM2G387528, GRMZM2G113779 and GRMZM2G017349) encode five network TFs with over-represented targets. (b) Topology of five TFs possessing over-represented targets in the network. TFs are represented as triangles and targets are represented as ellipses. Red colour indicates targets included in the network. Blue colour indicates targets outside of the network. (c) Expression profiles of GRMZM2G025642, GRMZM2G011357, GRMZM2G387528, GRMZM2G113779 and GRMZM2G017349 at four developmental stages in three tissues. a, Adjusted P-value ≤ 0.05.