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. 2017 Jul 27;8:146. doi: 10.1038/s41467-017-00142-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Histological analysis of ankle joints. Fresh-frozen sections (10 µm) of joints treated respectively with: a, BV^CAR alone; b, HAdV5-PUMA alone (10⁹ PFU); c, BV^CARHAdV5-PUMA (10⁷ PFU); d, BV^CARHAdV5-PUMA (10⁹ PFU); were stained with haematoxylin and eosin staining, and compared for the presence of synovial tissue infiltrates. The representative photograph from each group is provided at various magnifications (×200, left; ×400, middle; and ×800, right). The righmost panels are enlargements of the rectangular area delineated in the middle panels. Scale bar, 200 µm