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. 2017 Jul 26;7:6560. doi: 10.1038/s41598-017-06807-7

Table 1.

Gender, age and stage distribution of PBC from January 2001 to July 2016.

Period 1, 2001–2004 (n = 28) Period 2, 2005–2008 (n = 107) Period 3, 2009–2012 (n = 283) Period 4, 2013-July 2016 (n = 351) P
Sex 0.576
 Male 6 (21.4%) 15 (14.0%) 43 (15.2%) 45 (12.8%)
 Female 22 (78.6%) 92 (86.0%) 240 (84.8%) 306 (87.2%)
Age, years 0.068
 <40 0 (0%) 14 (13.1%) 26 (9.2%) 19 (5.4%)
 40–60 15 (53.6%) 59 (55.1%) 160 (56.5%) 214 (61.0%)
 >60 13 (46.4%) 34 (31.2%) 97 (34.3%) 118 (33.6%)
 Age, years 57.3 ± 9.7 54.1 ± 12.1 55.5 ± 12.2 55.6 ± 11.6 0.552
Stages
 Non-cirrhotic PBC 15 (53.6%) 50 (46.7%) 125 (44.2%) 130 (37.0%) 0.086
 Cirrhotic PBC 6 (21.4%) 25 (23.4%) 58 (20.5%) 56 (16.0%) 0.265
 Decompensated PBC 7 (25.0%) 32 (29.9%) 100 (35.3%) 165 (47.0%) 0.001
 Histological stages 4 9 15 60 0.276
 I–II 1 3 9 36
 III–IV 3 6 6 24