Table 2.
Changes in HRV parameters between the vagal response and non-vagal response groups.
| Parameter | Baseline | Post ablation | 1 month after ablationa | Relative change from baseline to post ablation (%) | Relative change from baseline to 1 month (%)a |
|---|---|---|---|---|---|
| Mean heart rate, bpm | |||||
| Vagal response | 58.1±7.2 | 71.7±5.9 | 60.7±9.1 | 24.6±15.6 | 12.2±15.7 |
| P (vs baseline) | <0.001 | 0.225 | |||
| Non-vagal response | 57.9±6.3 | 74.7±11.8 | 66.2±8.0 | 29.1±14.6 | 16.6±11.7 |
| P (vs baseline) | <0.001 | <0.001 | |||
| P (vs vagal response) | 0.912 | 0.424 | 0.233 | 0.402 | 0.524 |
| SDNN, ms | |||||
| Vagal response | 60.2±20.1 | 32.3±23.2 | 37.5±6.4 | −42.5±38.5 | −50.3±18.0 |
| P (vs baseline) | 0.009 | 0.040 | |||
| Non-vagal response | 64.1±24.4 | 25.8±12.6 | 32.9±11.9 | −56.8±20.0 | −44.8±23.9 |
| P (vs baseline) | <0.001 | <0.001 | |||
| P (vs vagal response) | 0.653 | 0.257 | 0.461 | 0.128 | 0.665 |
| rMSSD, ms | |||||
| Vagal response | 26.5±7.5 | 16.1±5.3 | 23.5±9.5 | −32.5±35.2 | −12.0±64.4 |
| P (vs baseline) | 0.008 | 0.429 | |||
| Non-vagal response | 30.8±15.4 | 16.4±5.9 | 20.9±8.8 | −37.6±30.3 | −19.2±48.1 |
| P (vs baseline) | <0.001 | 0.018 | |||
| P (vs vagal response) | 0.387 | 0.900 | 0.603 | 0.648 | 0.797 |
| Ln LF, ms2 | |||||
| Vagal response | 5.90±0.87 | 4.05±1.12 | 5.32±0.59 | −30.1±22.2 | −10.9±9.6 |
| P (vs baseline) | 0.001 | 0.089 | |||
| Non-vagal response | 5.95±0.83 | 3.78±1.22 | 4.64±1.21 | −35.2 ±22.2 | −22.3±19.0 |
| P (vs baseline) | <0.001 | <0.001 | |||
| P (vs vagal response) | 0.851 | 0.531 | 0.291 | 0.511 | 0.263 |
| Ln HF, ms2 | |||||
| Vagal response | 4.89±0.55 | 3.63±0.81 | 4.56±1.02 | −24.8±20.2 | −10.9±9.6 |
| P (vs baseline) | 0.002 | 0.438 | |||
| Non-vagal response | 4.94±0.86 | 3.56±0.80 | 4.13±0.94 | −26.3±18.3 | −12.8±21.9 |
| P (vs baseline) | <0.001 | 0.009 | |||
| P (vs vagal response) | 0.863 | 0.797 | 0.415 | 0.824 | 0.766 |
| LF/HF ratio | |||||
| Vagal response | 1.20±0.12 | 1.14±0.30 | 1.20±0.25 | −5.8±22.0 | 1.5±17.3 |
| P (vs baseline) | 0.414 | 0.832 | |||
| Non-vagal response | 1.22±0.15 | 1.06±0.30 | 1.14±0.28 | −13.1±21.7 | −8.1±21.4 |
| P (vs baseline) | 0.002 | 0.102 | |||
| P (vs vagal response) | 0.745 | 0.488 | 0.651 | 0.349 | 0.409 |
a
HRV analysis 1 month after the procedure was conducted with 4 and 20 patients in the vagal response and non-vagal response groups, respectively. HRV, heart rate variability; rMSSD, root-mean-square successive differences; SDNN, standard deviation of the NN intervals; LF, low frequency; HF, high frequency.