Table 1.
Variable | Whole cohort | T1a Stage | T1b Stage | T2 Stage | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
| ||||||||||||
NE | NSS | P | NE | NSS | P | NE | NSS | P | NE | NSS | P | |
Number of patients | 33292 | 22655 | 13309 | 18623 | 12705 | 3513 | 7278 | 519 | ||||
| ||||||||||||
Age (continuous) | 60.1 (12.6) | 58.6 (12.7) | <0.01 | 60.1 (12.6) | 58.4 (12.8) | <0.01 | 60.7 (12.5) | 59.6 (12.6) | <0.01 | 58.9 (12.5) | 59.1 (13.0) | 0.81 |
| ||||||||||||
Gender | ||||||||||||
Female | 13161 | 8613 | <0.01 | 5572 | 7255 | <0.01 | 4970 | 1186 | <0.01 | 2619 | 172 | 0.192 |
Male | 20131 | 14042 | 7737 | 11368 | 7735 | 2327 | 4659 | 347 | ||||
| ||||||||||||
Race | ||||||||||||
Black | 4091 | 2584 | 0.010 | 1765 | 2018 | <0.01 | 1416 | 476 | <0.01 | 910 | 90 | 0.005 |
White | 27026 | 18492 | 10727 | 15303 | 10421 | 2797 | 5878 | 392 | ||||
Other | 1943 | 1346 | 728 | 1105 | 777 | 209 | 438 | 32 | ||||
| ||||||||||||
Histology | ||||||||||||
ccRCC | 19627 | 12505 | <0.01 | 7938 | 10456 | <0.01 | 7751 | 1842 | <0.01 | 3938 | 207 | <0.01 |
Chromophobe type | 2182 | 1420 | 650 | 1099 | 750 | 265 | 782 | 56 | ||||
Papillary adenocar | 3629 | 3663 | 1562 | 2875 | 1223 | 671 | 844 | 117 | ||||
RCC unspecified | 6106 | 4069 | 2444 | 3391 | 2374 | 570 | 1288 | 108 | ||||
Other types | 1748 | 998 | 715 | 802 | 607 | 165 | 426 | 31 | ||||
| ||||||||||||
Tumor size (cm) | 5.4 (3.4) | 3.1 (2.0) | <0.01 | 2.9 (0.8) | 2.5 (0.8) | <0.01 | 5.5 (0.8) | 5.1 (0.8) | <0.01 | 10.0 (4.3) | 10.3 (7.6) | 0.39 |
| ||||||||||||
Grade | ||||||||||||
Grade I | 3971 | 3609 | <0.01 | 2099 | 3211 | <0.01 | 1353 | 352 | <0.01 | 519 | 46 | 0.195 |
Grade II | 16417 | 11034 | 6951 | 9210 | 6310 | 1621 | 3156 | 203 | ||||
Grade III | 7690 | 3658 | 2469 | 2633 | 3047 | 876 | 2174 | 149 | ||||
Grade IV | 1210 | 253 | 239 | 156 | 497 | 71 | 474 | 26 | ||||
| ||||||||||||
Laterality | ||||||||||||
Left | 16315 | 10997 | 0.283 | 6368 | 9045 | 0.204 | 6295 | 1676 | 0.055 | 3652 | 276 | 0.190 |
Right | 16970 | 11652 | 6937 | 9573 | 6410 | 1836 | 3623 | 243 | ||||
| ||||||||||||
RLN removed | ||||||||||||
No | 29867 | 22104 | <0.01 | 12560 | 18266 | <0.01 | 11515 | 3360 | <0.01 | 5792 | 478 | <0.01 |
Yes | 3378 | 514 | 729 | 331 | 1175 | 143 | 1474 | 40 | ||||
| ||||||||||||
Sequence number | ||||||||||||
One primary only | 29250 | 20045 | 0.026 | 11635 | 16540 | <0.01 | 11153 | 3066 | 0.417 | 6462 | 439 | 0.004 |
1st of 2 or more primaries | 4042 | 2610 | 1674 | 2083 | 1552 | 447 | 816 | 80 | ||||
| ||||||||||||
Marital status | ||||||||||||
Never married | 4881 | 3413 | <0.01 | 1881 | 2794 | <0.01 | 1843 | 534 | 0.133 | 1157 | 85 | 0.384 |
Ever married | 6325 | 3789 | 2588 | 3057 | 2463 | 632 | 1274 | 100 | ||||
Married | 20605 | 14336 | 8269 | 11841 | 7818 | 2192 | 4518 | 303 | ||||
| ||||||||||||
Vital status | ||||||||||||
Alive | 28205 | 20979 | <0.01 | 11441 | 17384 | <0.01 | 10771 | 3150 | <0.01 | 5993 | 445 | 0.049 |
Dead | 5087 (0.1528) | 1676 (0.0740) | 1868 (0.1404) | 1239 (0.0665) | 1934 (0.1522) | 363 (0.1033) | 1285 (0.1766) | 74 (0.1426) |
NE – nephrectomy; ccRCC – clear cell renal cell carcinoma; Papillary adenocar – Papillary adenocarcinoma; RLN – regional lymph nodes. Sequence number: The sequence of renal cell carcinoma of all reportable tumors which occur over the lifetime of a patient. Ever married consisted Divorced, Separated and Widowed. Missing values were omitted for some variables.