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. Author manuscript; available in PMC: 2017 Nov 20.
Published in final edited form as: J Mol Biol. 2016 Aug 14;428(23):4626–4638. doi: 10.1016/j.jmb.2016.08.012

Figure 5.

Figure 5

Examination of nucleotide sequence effect for deaminase using DNA substrate containing N-CpG-N or N-mCpG-N (the underlined C and mC are deamination target residue, and N being any nucleotide). (A) The deaminase activity of A3H hap II on the N-mC pG-N substrates, showing that T-mCpG-C/G are the best substrate. Error bars represent s.d. from the mean of three independent replicates. (B) The deaminase activity of A3H hap II on the N-CpG-N containing substrates, showing that T-CpG-C/G/A are the best substrates than others.