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HLA B27-restricted KK10 responses in HIV-infected controls. The pie charts depict the CD8+ T cell response to KK10 (a) in 2714A and 3963I and HIV Gag (b) in 2714A. The value in the center of each pie chart represents the total response to the respective stimuli. (c) Infection-induced KK10-specific CD8+ T cells have a predominant effector/effector memory phenotype. Red contour overlays depict the B27 KK10 tetramer+ CD8+ T cells, whereas the blue density plot depicts total CD8+ T cells.
