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. 2017 Jun 8;14(2):1333–1340. doi: 10.3892/ol.2017.6347

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Copyright: © Feng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 8. — Effect of ERK1/2 and JNK inhibitors on the invasiveness of MG63/dox cells. A Transwell assay was used to assess the invasion ability of MG63/dox cells treated with As₂O₃ and ADM, PD098095, or As₂O₃ and ADM with SP600125. *P<0.05 compared with control group;^#P<0.05 compared with the As₂O₃ and ADM group. ERK1/2, mitogen-activated protein kinase 3/1; JNK, mitogen-activated protein kinase 8; MG63/dox, MG63/doxorubicin-resistant; As₂O₃, arsenic trioxide; ADM, doxorubicin.