Kaplan-Meier curves demonstrating OS in patients with OSCC according to WISP-1 expression. High WISP-1 expression tended to decrease OS in patients with OSCC, however log-rank tests did not demonstrate a significant difference between these patients with high and low expression of WISP-1 (P=0.075 vs. low expression). Solid line, patients with low WISP-1 expression; dotted line, patient with high WISP-1 expression. OS, overall survival; OSCC, oral squamous cell carcinoma; WISP-1, WNT1-inducible-signaling pathway protein-1.