Figure 3.

WISP-1 knockdown by siRNA in human OSCC cells. WISP-1 mRNA and protein were expressed in SCC-1483 OSCC cells. WISP-1 mRNA and protein expression were significantly reduced following transfection with WISP-1 siRNA in OSCC cells compared with the negative control. *P<0.05. GAPDH, glyceraldehyde 3-phosphate dehydrogenase; C, negative control siRNA-transfected cells; W, WISP-1-specific siRNA-transfected cells; WISP-1, WNT1-inducible-signaling pathway protein-1; siRNA, small interfering RNA; OSCC, oral squamous cell carcinoma.