Table I.
Comparison of the patient background between the DPD-positive and DPD-negative groups.
| Characteristic | Patients exhibiting positive DPD expression (n=34) | Patients exhibiting negative DPD expression (n=32) | P-value |
|---|---|---|---|
| Median age, years (range) | 71 (50–80) | 66 (51–81) | 0.266 |
| Sex | 0.025 | ||
| Male | 23 (67.6%) | 13 (40.6%) | |
| Female | 11 (32.4%) | 19 (59.4%) | |
| Surgical procedure | 0.235 | ||
| PD | 24 (70.6%) | 16 (50.0%) | |
| DP | 8 (23.5%) | 11 (34.4%) | |
| TP | 2 (5.9%) | 5 (15.6%) | |
| Median size of tumor, mm (range) | 34.5 (18–105) | 40 (15–80) | 0.718 |
| Pathological type | 0.708 | ||
| tub1 | 20 (58.8%) | 19 (59.4%) | |
| tub2 | 10 (29.4%) | 8 (25.0%) | |
| por | 3 (8.8%) | 2 (6.3%) | |
| Others | 1 (2.9%) | 3 (9.4%) | |
| Pathological T factor | 0.163 | ||
| T2 | 1 (2.9%) | 0 (0.0%) | |
| T3 | 32 (94.1%) | 32 (100.0%) | |
| T4 | 1 (2.9%) | 0 (0.0%) | |
| Pathological N factor | 0.351 | ||
| N0 | 11 (32.4%) | 6 (18.8%) | |
| N1 | 23 (67.6%) | 26 (81.3%) | |
| Stage (7th UICC classification) | 0.351 | ||
| IIA | 11 (32.4) | 6 (18.8) | |
| IIB | 22 (64.7%) | 26 (81.3%) | |
| III | 1 (2.9%) | 0 (0.0%) |
DPD, dihydropyrimidine dehydrogenase; PD, pancreaticoduodenectomy; DP, distal pancreatectomy; TP, total pancreatectomy; tub1, well-differentiated tubular adenocarcinoma; tub2, moderately differentiated tubular adenocarcinoma; por, poorly differentiated adenocarcinoma; T, tumor; N, node; UICC, Union for International Cancer Control.