Table III.
Univariate and multivariate analyses of risk factors for the overall survival rates of patients exhibiting high DPD expression compared with those exhibiting low DPD expression.
| Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|
| Factor | n | OR | 95% CI | P-value | OR | 95% CI | P-value |
| Sex | 0.662 | ||||||
| Female | 30 | 1 | |||||
| Male | 36 | 1.177 | 0.567–2.441 | ||||
| Age, years | 0.532 | ||||||
| <70 | 29 | 1 | |||||
| ≥70 | 37 | 1.259 | 0.612–2.587 | ||||
| Size of tumor, mm | 0.352 | ||||||
| <38 | 33 | 1 | |||||
| ≥38 | 33 | 1.42 | 0.678–2.974 | ||||
| Tumor location | 0.239 | ||||||
| Body or tail | 19 | 1 | |||||
| Head | 47 | 1.709 | 0.700–4.169 | ||||
| Pathological N factor | 0.034 | ||||||
| N0 | 17 | 1 | |||||
| N1 | 49 | 3.627 | 1.099–11.971 | ||||
| DPD status | 0.023 | 0.02 | |||||
| Low | 48 | 1 | 1 | ||||
| High | 18 | 3.078 | 1.164–8.135 | 3.183 | 1.197–8.467 | ||
DPD, dihydropyrimidine dehydrogenase; OR, odds ratio; CI, confidence interval; N, node.