Table II.
Univariate and multivariate analysis of clinicopathological factors affecting overall survival rate.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Factors | RR | 95% CI | P-value | RR | 95% CI | P-value |
| Age (≥65/<65) | 0.93 | 0.46–1.91 | NS | 1.68 | 0.58–5.15 | NS |
| Sex (male/female) | 1.19 | 0.45–4.13 | NS | 1.21 | 0.26–7.54 | NS |
| Histology grade (well/moderate and poor) | 0.62 | 0.24–1.51 | NS | 1.89 | 0.59–5.66 | NS |
| T factor (T1/T2-4) | 0.31 | 0.07–0.94 | <0.05 | 0.22 | 0.03–1.11 | NS |
| Lymph node metastasis (negative/positive) | 0.43 | 0.17–0.98 | <0.05 | 0.53 | 0.11–1.92 | NS |
| Lymphatic invasion (negative/positive) | 5.42×10−10 | 0.34–2.96 | <0.005 | 3.37×10−10 | 0.47–2.11 | <0.05 |
| Venous invasion (negative/positive) | 6.02×10−10 | 0.48–2.08 | <0.05 | 1.67×10−9 | 0.37–2.68 | NS |
| Distant metastasis (negative/positive) | 5.84 | 0.92–20.79 | NS | 11.01 | 0.51–23.34 | NS |
| ZNF750 mRNA expression (high/low) | 3.83 | 1.82–8.59 | <0.0005 | 3.83 | 1.22–13.44 | <0.05 |
RR, relative risk; CI, confidence interval; NS, not significant; T, Depth of tumor invasion.