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. 2015 Oct 26;7(1):728–736. doi: 10.1039/c5sc01698c

Fig. 5. (a) Orthogonal views of MSOT images of C26 tumor-bearing mice at 24 h following injection of IR830-labeled A15-PGA-CisPt with or without DMXAA (DMXAA dosage: 15.0 mg kg–1). The 3D coordinate system defines the orientations and positions of the orthogonal views. B and T represent the bladder and tumor regions, respectively. (b) Pt accumulation in C26 tumors at 24 h following administration of free cisplatin (4.0 mg kg–1), A15-PGA-CisPt (4.0 mg cisplatin equivalent per kg), or DMXAA (15.0 mg kg–1) + A15-PGA-CisPt (4.0 mg cisplatin equivalent per kg) (n = 4, **: p < 0.01, ***: p < 0.001).

Fig. 5