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(A) RMSF of the EGFR wild-type (black) and mutant (red). The important residues of ATP binding and active site are marked. (B) The b-factor implicated on the average structures of the wild-type and mutant EGFR, clearly indicating the mutant structure to be more fluctuating in nature. RMSF, root mean square fluctuation; ATP, adenosine triphosphate; EGFR, epidermal growth factor receptor.
