Skip to main content
. 2017 Jul 20;12:2095–2100. doi: 10.2147/COPD.S140299

Table 2.

Risk factors for incident hypoxic respiratory failure

Univariable logistic regression
Multivariable logistic regression
OR (95% CI) P-value OR (95% CI) P-value
Female 0.92 (0.52–1.61) 0.76 0.53 (0.24–1.17) 0.12
Age (per 1 year) 1.01 (0.98–1.05) 0.42 1.02 (0.97–1.07) 0.40
FEV1 (per 1 L) 0.08 (0.04–0.17) <0.0001 0.89 (0.03–0.30) <0.0001
CAT score (per 1 point) 1.13 (1.08–1.18) <0.0001 1.07 (1.02–1.13) 0.007
BMI (kg/m2)
 <22 0.41 (0.21–0.78) 0.007 2.25 (0.95–5.33) 0.07
 22–29 Ref Ref
 ≥30 0.74 (0.35–1.56) 0.43 1.90 (0.71–5.09) 0.20
 Heart disease 0.89 (0.35–2.25) 0.80 0.48 (0.14–1.70) 0.26
 Sleep apnea syndrome 3.59 (1.08–11.9) 0.037 4.79 (0.94–24.3) 0.06
mMRC*
 2 1.65 (0.57–4.79) 0.36 0.61 (0.17–2.21) 0.45
 3 2.99 (1.08–8.29) 0.036 0.47 (0.12–1.85) 0.28
 4 11.4 (5.03–25.9) <0.0001 0.84 (0.23–3.04) 0.79

Notes: Results from logistic regression with hypoxic respiratory failure at follow-up as the dependent variable.

*

The estimates of mMRC are from univariable analysis, and multivariable analysis with all independent variables above and with further adjustment for mMRC.

Abbreviations: BMI, body mass index; CAT, COPD assessment test; FEV1, forced expiratory volume in 1 second; mMRC, modified Medical Research Council; OR, odds ratio; Ref, reference category.