Table I.
Altered expression of genes involved in cellular proliferation and apoptosis.
| Fold change (vs. PC-9) | ||||
|---|---|---|---|---|
| Gene symbol | Description | Genbank | PC-9G | PC-9E |
| Upregulated | ||||
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | NM_004723 | 1.52 | 2.29 |
| INPP5D | Inositol polyphosphate-5-phosphatase, 145 kDa | NM_001017915 | 3.49 | 5.22 |
| Downregulated | ||||
| ADORA1 | Adenosine A1 receptor | NM_000674 | −2.90 | −5.15 |
| CD24 | CD24 molecule | NM_013230 | −1.91 | −4.39 |
| CLU | Clusterin | NM_001831 | −3.24 | −1.79 |
| EGLN3 | Egl-9 family hypoxia-inducible factor 3 | NM_022073 | −1.59 | −2.18 |
| F2R | Coagulation factor II (thrombin) receptor | BC016059 | −5.15 | −1.68 |
| IL6 | Interleukin 6 (interferon, β2) | NM_000600 | −1.65 | −1.49 |
| MAGED1 | Melanoma antigen family D, 1 | NM_001005333 | −1.86 | −2.08 |
| NTN1 | Netrin 1 | NM_004822 | −1.63 | −2.68 |
| PHB | Prohibitin | NM_002634 | −2.07 | −1.58 |
| PRKRA | Protein kinase, interferon-inducible double stranded RNA dependent activator | NM_003690 | −2.74 | −1.43 |
| SMO | Smoothened frizzled class receptor | NM_005631 | −3.72 | −10.07 |
| TGM2 | Transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | NM_198951 | −1.81 | −2.02 |
| TNFRSF14 | Tumor necrosis factor receptor superfamily, member 14 | AB208808 | −1.76 | −2.05 |
| TNFRSF8 | Tumor necrosis factor receptor superfamily, member 8 | NM_001243 | −2.78 | −2.27 |